A Beginner's Guide to Naproxen

Naproxen is a widely used non-steroidal anti-inflammatory drug (NSAID) that helps relieve pain, swelling and stiffness caused by various conditions. It’s commonly prescribed for joint disorders, period pain and muscle or bone injuries. Whether you’re taking Naproxen for the first time or simply want to understand how it works, this guide explains everything you need to know, including how it works, how to take it safely, possible side effects and when it’s suitable to use.

In One Sentence:

“Naproxen is a prescription anti-inflammatory medicine used to relieve pain and swelling in conditions such as arthritis, gout and period pain by reducing inflammation and blocking pain signals in the body”.

Key Takeaways

Here are the five biggest takeaways from this article about Naproxen:

• Naproxen is a non-steroidal anti-inflammatory medicine (NSAID) used to treat pain, inflammation and stiffness caused by conditions such as arthritis, gout and period pain.

• It works by reducing prostaglandin production, chemicals responsible for inflammation and pain.

• Common side effects include indigestion and heartburn, while serious side effects, such as stomach ulcers, are rare but require medical attention.

• It should usually be taken with food and water to reduce stomach irritation.

• Naproxen is available on prescription in the UK, while lower-strength versions can be purchased over the counter for period pain.

What is Naproxen, and what is it used for?

Naproxen is a medicine from the non-steroidal anti-inflammatory drug (NSAID) family. It helps reduce inflammation, pain and swelling in the body. In the UK, it is available only on prescription for most uses, though lower doses are available in some over-the-counter products for period pain.

Naproxen is used to treat several conditions, including:

• Rheumatoid arthritis and osteoarthritis

• Gout

• Ankylosing spondylitis

• Muscle, bone and joint pain (such as strains or sprains)

• Period pain

It can also be used short-term for pain relief after surgery or injury.

How does Naproxen work?

Naproxen works by blocking enzymes in the body called cyclo-oxygenase (COX). These enzymes help produce prostaglandins, which cause pain and inflammation. By reducing prostaglandin production, Naproxen helps to ease pain, reduce swelling and lower fever.

The table below summarises how Naproxen acts on specific conditions:

Naproxen dosage and how to take it

Naproxen should be taken as prescribed by your doctor. The dose will vary depending on your condition and medical history. It’s best taken with or after food, with a full glass of water. This helps protect the stomach from irritation [1].

Below are typical dosage guidelines for different conditions:

Do not exceed the prescribed dose, and always follow your doctor’s advice.

Naproxen side effects

Like all medicines, Naproxen can cause side effects, though not everyone experiences them [2]. Most are mild and improve as your body adjusts, but some can be serious.

If you experience any unusual or severe symptoms, seek medical attention straight away.

Warnings and precautions

Naproxen may not be suitable for everyone. You should inform your doctor before taking it if you [3]:

• Have or have had stomach ulcers, bleeding, or digestive issues

• Have heart disease, high blood pressure, or kidney problems

• Are pregnant, breastfeeding, or planning a pregnancy

• Are over 65, as you may be more at risk of side effects

• Are taking other NSAIDs such as ibuprofen or aspirin

Children and teenagers under 16 should not take Naproxen unless prescribed by a specialist.

Interactions

Naproxen can interact with several medicines, which may increase the risk of side effects or reduce its effectiveness. Always tell your doctor or pharmacist about other medicines you are taking, including herbal supplements [4].

Common interactions include:

• Other NSAIDs (such as ibuprofen or aspirin)

• Blood-thinning medicines (such as warfarin)

• Medicines for high blood pressure (like ACE inhibitors)

• Corticosteroids

• Some antidepressants (SSRIs)

Avoid taking more than one NSAID at a time unless advised by your doctor.

Who can take Naproxen? (Eligibility Criteria in the UK)

Most adults aged 18 and over can take Naproxen if prescribed by a healthcare professional. It may also be suitable for teenagers aged 12 to 17 for specific conditions under medical supervision.

However, it might not be suitable if you:

• Have liver, kidney, or heart problems

• Have previously reacted to aspirin or other NSAIDs

• Are pregnant or breastfeeding

• Have a history of stomach or digestive issues

Always check with your doctor or pharmacist before starting Naproxen.

Naproxen Cost in the UK

Prices for Naproxen can vary depending on the strength and supplier. The table below shows prices available through UK Meds at the time of writing (prices are subject to change).

Naproxen FAQs

How long does Naproxen take to work?

You should begin to feel relief within one hour of taking Naproxen, although it may take several days of regular use for the inflammation to reduce entirely.

Can I drink alcohol while taking Naproxen?

You can drink alcohol in moderation, but excessive alcohol may irritate your stomach or increase the risk of side effects such as ulcers or bleeding.

Can I take Naproxen with paracetamol?

Yes, Naproxen can usually be taken with paracetamol for short periods, but avoid combining it with other anti-inflammatory medicines such as ibuprofen.

Should I take Naproxen with food?

Yes. Taking Naproxen with or after food, and with a full glass of water, helps reduce the risk of stomach upset.

Can I buy Naproxen over the counter in the UK?

Yes. A low-dose version is available over the counter for period pain (for example, Feminax Ultra), but higher-strength versions require a prescription.

Final Thoughts

Naproxen is an effective and reliable pain-relief option for various inflammatory conditions, including gout. When taken correctly and under medical supervision,  it can help manage symptoms and improve quality of life. However, like all medicines, it should be used responsibly, with awareness of possible side effects and interactions. Always follow your doctor’s advice and report any unusual symptoms.

Sources

[1] How and when to take naproxen - NHS

[2] Side effects of naproxen - NHS

[3] Who can and cannot take naproxen - NHS

[4] Taking naproxen with other medicines and herbal supplements - NHS