Xigduo (Dapagliflozin / Metformin Hydrochloride)

GP and surgeon, Dr Shane Charles (MBBS, MRCS, PgDip SEM) provides a simple explanation of the medication below:

'Xigduo is a combined antidiabetic medication comprised of dapagliflozin and metformin, and works to lower blood sugar levels. '.

If you think Xigduo is a treatment that can help you, start an online consultation now for a registered prescriber to review. If treatment is deemed suitable, they can prescribe it, and we can deliver it to you from the comfort of your own home with a range of convenient delivery and payment options for you to choose from. If you have any questions about a medication, you should always consult your doctor with any questions prior to starting treatment, to ensure that it is safe and suitable for you.

How Can I Buy Xigduo Online?

You can safely purchase Xigduo online from UK Meds. Before your order is approved, you’ll need to complete a quick online consultation with a registered independent prescriber. This ensures that Xigduo is the right medication for your condition and that it is safe for you to use.

What is Xigduo?

Xigduo is a prescription medication used to help control blood sugar levels in people with type 2 diabetes. It is an oral anti-diabetic that works alongside diet and exercise to help manage the condition.

How Does Xigduo Work?

In type 2 diabetes, the pancreas doesn’t produce enough insulin, or the body can’t use it effectively. This leads to high blood sugar levels, which can cause serious health issues. Xigduo helps lower and regulate blood sugar to keep it within a healthy range.

What Are the Benefits of Taking Xigduo?

Type 2 diabetes can cause symptoms like extreme thirst, frequent urination, and fatigue. If left untreated, it can lead to complications affecting the eyes, heart, and nervous system. Xigduo helps reduce these risks by keeping blood sugar levels stable.

Xigduo Reviews

Read first hand what other patients think about Xigduo and it's impact on patients lives on the reviews available at Drugs.com and Web MD.

It is important to note that people may have different experiences when they use Xigduo. If someone states that their medication did not work as they had hoped, it does not mean that it will not work for you. If you believe that it is the right medication for you then the best thing to do is to consult your doctor or healthcare professional, and judge the medication based on your own experiences if they recommend it as a treatment. Before starting a medication you should always consult with your healthcare provider first to ensure that it is safe and suitable for your individual needs.

For more information on the prescription medication patients should refer to the Xigduo patient information leaflet.

How Do I Use Xigduo?

Xigduo is a prescription-only medicine, so you should always follow your doctor’s instructions and read the patient information leaflet that comes with it.

Take one tablet whole with a glass of water, ideally with food to reduce the risk of an upset stomach. While you can take it at any time of day, it’s best to take it at the same time every day to help you remember.

What Is the Recommended Dosage for Xigduo?

Xigduo contains dapagliflozin and metformin, available in two strengths: 5 mg/850 mg or 5 mg/1,000 mg per tablet.

The usual dose is one tablet twice a day, but your doctor will decide the right dose based on your needs.

Missed a Dose?

• If you forget a dose, take it as soon as you remember.
• If it’s nearly time for your next dose, skip the missed one and take your next tablet as normal.
• Never take two tablets at once to make up for a missed dose.

What If You Take Too Much?

Taking too much Xigduo can cause lactic acidosis, a serious condition that requires immediate medical attention. Go to A&E or see a doctor straight away if you experience:

• Feeling or being sick
• Stomach pain with muscle cramps
• Extreme tiredness
• Breathing difficulties

What Side Effects Can Xigduo Have?

Like all medicines, Xigduo can cause side effects, but not everyone will experience them. Some side effects can be serious, so it's important to know what to look out for.

Stop Taking Xigduo and Seek Medical Help Immediately If You Experience:

Lactic Acidosis (Very Rare - Up to 1 in 10,000 People)

This is a serious condition that requires urgent medical attention. Signs include:

• Feeling or being sick
• Stomach pain with muscle cramps
• Severe tiredness
• Breathing difficulties
• Feeling cold or lightheaded

Diabetic Ketoacidosis (Rare - Up to 1 in 1,000 People)

Even if your blood sugar is normal, diabetic ketoacidosis can occur. Signs include:

• Rapid weight loss
• Extreme thirst
• Feeling sick or vomiting
• Stomach pain
• Fast breathing
• Feeling confused, tired, or drowsy
• A sweet smell on your breath or urine

Fournier’s Gangrene (Very Rare)

This is a serious infection affecting the genitals or area between the genitals and anus. Seek immediate medical attention if you notice redness, pain, swelling, or fever.

Other Side Effects to Watch Out For:

Common Side Effects (Up to 1 in 10 People)

• Urinary tract infection (burning sensation when urinating, fever, chills, back pain)
• Genital infections (thrush) (itching, irritation, unusual discharge)
• Feeling dizzy or tired
• Changes in blood tests (cholesterol, red blood cells, vitamin B12 levels)
• More frequent urination

Uncommon Side Effects (Up to 1 in 100 People)

• Dry mouth or excessive thirst
• Constipation
• Weight loss

Very Rare Side Effects (Up to 1 in 10,000 People)

• Liver problems (hepatitis, inflammation, or abnormal liver tests)
• Skin reactions (redness, itching, hives)

Low Blood Sugar Warning (When Taken with Certain Medicines)

Xigduo can cause low blood sugar (hypoglycaemia) if taken with other diabetes medications like insulin or sulphonylureas. Signs include:

• Shaking, sweating, dizziness
• Fast heartbeat and feeling anxious
• Extreme hunger or headache

How to Treat Low Blood Sugar:

• Eat glucose tablets or a high-sugar snack
• Drink fruit juice
• Rest and check your blood sugar levels

How to Report Side Effects

If you experience any side effects, speak to your doctor, pharmacist, or nurse. You can also report side effects to the MHRA Yellow Card Scheme at www.mhra.gov.uk/yellowcard or via the MHRA Yellow Card app on Google Play or the Apple App Store.

By reporting side effects, you help improve the safety of this medication for others.

• How and When to Take Dapagliflozin with Metformin - NHS
• Dapagliflozin with Metformin - BNF

• What's the Difference Between Type 1 and Type 2 Diabetes? - Learn about the key differences between Type 1 and Type 2 diabetes and how they affect the body.
• Guide to Prediabetes: Causes, Symptoms, and Treatments - Understand what prediabetes is, its causes, symptoms, and how to manage it before it develops into full-blown diabetes.
• Type 2 Diabetes Treatment and Testing Guide - A comprehensive guide on how Type 2 diabetes is treated and how to monitor your blood sugar levels.
• What Are the Different Types of Diabetes Medication? - Explore the different types of medications used to manage diabetes and how they work.
• New Year's Resolution: Managing Your Diabetes - Learn how setting goals and making lifestyle changes can help you manage your diabetes better in the new year.
• Do I Have Diabetes? Quiz - Take this quiz to help determine if you may have diabetes and if you should get tested.