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NAD+ Injections

Support Your Cellular Health & Energy

NAD+ (Nicotinamide Adenine Dinucleotide) is a vital coenzyme found in every cell of the body. It plays a key role in energy production, DNA repair and cellular communication. As we age, NAD+ levels naturally decline, which can impact overall health and contribute to ageing-related conditions. Maintaining optimal NAD+ levels through NAD+ therapy such as using self-administered NAD+ injections and supplements can support cellular regeneration, cognitive function, metabolic health, and overall well-being.

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Boost Your Wellness with Self-Injection NAD+ Pens

Support your energy, focus, and overall health with NAD+ self-injection pens.

NAD+ (Nicotinamide Adenine Dinucleotide) is a natural substance found in every cell of your body. It helps create energy, repair cells, and keep your brain and body working at their best. But as we age, NAD+ levels drop, which can lead to tiredness, brain fog, and slower recovery.

UK Meds makes it easy to feel your best. Our NAD+ pens are simple to use at home, giving you the flexibility to boost your wellbeing on your own schedule – without the need for a clinic visit.

Want to boost your energy, stay mentally sharp, and age in a healthier way? NAD+ therapy could help.

What is NAD+ Therapy?

NAD+ (short for Nicotinamide Adenine Dinucleotide) is a natural molecule found in every cell of your body. It helps turn the food you eat into energy, repairs cells, and keeps your brain and body working as they should.

As you age, your NAD+ levels naturally fall. This drop can leave you feeling tired, foggy-headed, slower to recover after exercise, and generally low in energy. NAD+ therapy works by boosting these levels, helping your body feel stronger, sharper, and more refreshed.

Restoring NAD+ may help you feel more energised, focused, and clear-headed, while also supporting healthy ageing and your long-term wellbeing.

Who Can Benefit from NAD+ Therapy?

NAD+ therapy may be right for you if you're feeling low on energy, struggling with focus, or want to support healthy ageing.

If you're unsure whether NAD+ therapy is right for you, our team can guide you based on your personal health goals and lifestyle.

Scientific Evidence Supporting NAD+ Therapy

Research into NAD+ therapy is growing, with studies highlighting its potential to support various aspects of health and ageing:

  • Energy metabolism: Studies show that NAD+ is vital for mitochondrial function and ATP production, directly influencing how energised you feel[1].
  • Brain function: NAD+ may support cognitive performance and protect neurons against age-related damage [7].
  • Cell repair: NAD+ activates sirtuins, a group of proteins that help repair DNA and regulate ageing [8].
  • Anti-ageing benefits: Animal studies have linked higher NAD+ levels with improved lifespan and delayed age-related decline [9].

What Are NAD+ Injections?

NAD+ injections are a quick and effective way to boost your body’s levels of Nicotinamide Adenine Dinucleotide (NAD+), an essential molecule that helps power your cells. Also known as 'NAD shots', these injections are popular for health optimisation, longevity, and anti-ageing[1][2].

Whether through a full NAD+ infusion or a quick NAD shot, these injectable treatments deliver NAD+ directly into the bloodstream, where it may help support:

  • Better energy production at the cellular level
  • Sharper brain function and clearer thinking
  • Healthy ageing and DNA repair
  • Faster recovery from stress, tiredness, or illness

Many people choose regular NAD shots to maintain energy, boost focus, and support their long-term wellbeing. NAD+ injections are widely used by those taking a proactive approach to health.

Understanding NAD+ (Nicotinamide Adenine Dinucleotide)

NAD+ is a coenzyme found in every cell of your body [3][4]. It plays a key role in:

  • Converting food into usable energy (ATP)
  • Repairing damaged DNA and maintaining cell health
  • Supporting metabolism and mitochondrial function
  • Activating longevity-related proteins (sirtuins)

Without enough NAD+, your cells may struggle to perform basic functions—leading to fatigue, brain fog, and signs of premature ageing.

Is NAD the same as NAD+?

No, NAD and NAD+ are related, but they’re not exactly the same. NAD (nicotinamide adenine dinucleotide) is the general name for a molecule that exists in two forms: NAD+ and NADH.

NAD+ is the active form your body uses in important processes like turning food into energy and repairing DNA. It works by picking up electrons and changing into NADH. NADH then gives away those electrons during other reactions and turns back into NAD+.

This back-and-forth cycle helps your cells stay healthy and energised.

Why NAD+ Levels Decline With Age

As we get older, our natural NAD+ levels start to drop. This decline can be made worse by:

  • Stress and poor sleep
  • Excess alcohol or sugar consumption
  • Chronic illness or inflammation
  • Exposure to toxins and pollutants

This reduction in NAD+ has been linked to age-related health issues such as low energy, weakened immunity, poor memory, and reduced cellular repair [5][2].

What Makes Injectable NAD+ Different From Pills or Patches?

While NAD+ supplements come in various forms, such as capsules, patches, or oral treatments, injectables offer unique benefits in terms of speed and effectiveness.

FormAbsorptionOnset TimeTypical Use
NAD+ InjectionsHigh – it goes directly into bloodstreamFast – often within hoursTargeted energy boost, brain support, anti-ageing
NAD+ PillsLow to moderate – can be affected by digestionSlower – may take weeks to notice effectsGeneral daily support
NAD+ PatchesModerate – absorbed through skinModerate – gradual releaseConvenient but less potent than injections

NAD+ injections are often chosen by people who want noticeable results quickly, especially if they are feeling run-down, have demanding lifestyles, or are actively pursuing wellness and longevity goals.

How Do NAD+ Injections Work in the Body?

NAD+ injections deliver this essential coenzyme straight into your bloodstream, where it can quickly get to work supporting your cells. Unlike oral supplements, which must pass through the digestive tract, injections allow NAD+ to be absorbed directly and efficiently.

The Role of NAD+ in Cellular Energy (ATP) Production

Every cell in your body relies on NAD+ to generate energy. It does this by helping your mitochondria (the powerhouses of your cells) convert nutrients into ATP, your body’s main energy currency1.

Without enough NAD+, your cells may struggle to:

  • Maintain normal energy levels
  • Carry out vital functions such as repair and regeneration
  • Combat oxidative stress and inflammation

This is why NAD+ therapy is often associated with improved energy, clearer thinking, and better overall vitality [6].

How Injecting NAD+ Bypasses the Digestive System

When taken by mouth, NAD+ must be broken down by the digestive system and absorbed through the gut. This process can reduce how much of the active ingredient actually makes it into your bloodstream.

With injections, NAD+ bypasses the digestive system entirely and enters the bloodstream directly. This offers several key benefits:

  • Higher absorption and bioavailability
  • Faster onset of effects – often within hours
  • More predictable and consistent results

This makes injectable NAD+ ideal for people who need quick, noticeable support, whether for brain fog, fatigue, stress, or active recovery.

Injections vs NAD+ Oral Capsules

NAD+ capsules are widely available and easy to use, but they may not work as quickly or effectively as injections.

FeatureNAD+ InjectionsNAD+ Capsules
AbsorptionHigh – goes straight into the bloodstreamLow to moderate – affected by your gut health
Speed of EffectFast – some people feel the difference within hoursSlower – may take a few weeks of daily use
BioavailabilityVery high – little is lost in the processLower – broken down during digestion
ConvenienceNeeds a self-injection or clinic visitEasy – take one daily with water

Oral capsules are a good choice if you want something quick and easy. But if you're looking for faster or stronger effects, NAD+ injections may be more suitable. Everyone's body is different, so results can vary.

NAD+ Injections vs NMN and NR (Precursors)

NMN (Nicotinamide Mononucleotide) and NR (Nicotinamide Riboside) are common supplements known as NAD+ precursors. This means your body has to convert them into NAD+ before they can be used.

  • NMN/NR: Go through several conversion steps in the body. How well this works can depend on your age and overall health.
  • NAD+ Injections: Deliver NAD+ directly in its active form, so your body can use it straight away without any conversion.

NMN and NR can be helpful for everyday support. But if you want quicker or stronger results, such as during times of stress, tiredness, or age-related decline, NAD+ injections may be more effective.

Injections vs IV Drips

Both injections and IV drips deliver NAD+ straight into your bloodstream, but the main difference is how and where you take them:

  • IV Drips: Usually done in a clinic. They take 1-2 hours and are often used for high doses or longer treatment plans.
  • Injections: Quick and easy to do at home. They only take a few minutes and offer more flexibility.

Injections are ideal if you want a convenient and time-saving way to get the same potential benefits without going to a clinic.

Which NAD+ Option Is Best for Me?

The right choice depends on your health goals, lifestyle, and personal preferences. Here's a simple guide:

GoalRecommended Option
Quick energy or mental clarityNAD+ Injections
Daily support and general wellbeingNAD+ Capsules or NR/NMN Supplements
High-dose or long-term treatmentIV Drip (in-clinic)
Ageing support over timeInjections or NMN (based on preference)

If you're not sure which option is right for you, speak to a registered healthcare professional or book a clinical consultation. Everyone's needs are different, so it's best to get advice tailored to your health and goals.

What are the benefits of NAD+ Injections?

NAD+ injections offer a range of health benefits by boosting your body’s natural energy and repair systems. Here’s a quick look at how they can help:

BenefitHow It Helps
Anti-ageing SupportHelps repair damaged cells, reduce oxidative stress, and slow signs of ageing by supporting cell health.
More EnergyBoosts energy by improving how your cells create fuel (ATP), helping to fight tiredness and fatigue.
Sharper ThinkingMay improve memory, focus, and mental clarity by supporting brain cell function.
Metabolism BoostSupports how your body processes food and breaks down fats, which can help with weight management.
Stronger Immune SystemHelps your body fight off illness by supporting your natural immune defences.
Better Athletic RecoveryMay reduce recovery time and improve stamina by supporting muscle repair and energy production.
Overall WellbeingSupports general health by helping your cells function better and making you feel more balanced and energised.

Lifestyle Tips to Naturally Support NAD+ Levels

NAD+ injections can give your body a quick boost, but your everyday habits also matter. Simple lifestyle changes can help your body make and maintain healthy NAD+ levels over time. This may support long-term cell health and slow the natural drop in NAD+ that comes with ageing.

Diet and Foods That May Help Boost NAD+

Eating a balanced diet with plenty of B vitamins can help your body make more NAD+. Nutrients like niacin (vitamin B3) and tryptophan are key building blocks your cells use to create it [12].

Foods that may support NAD+ production:

  • Avocados – packed with B vitamins and healthy fats
  • Oily fish (like salmon, mackerel, and sardines) - rich in B vitamins and support energy production in cells
  • Dairy products (like yoghurt and cheese) - contain both niacin and tryptophan
  • Leafy greens - such as spinach and kale, full of antioxidants
  • Whole foods over processed grains - better for reducing inflammation and supporting overall health

Drinking enough water and cutting down on sugar, alcohol, and processed foods can also support healthy NAD+ levels and metabolism.

Exercise and Sleep for Cellular Health

Consistent exercise and proper sleep are essential for maintaining the optimal function of your mitochondria and NAD+ [13][14][15][16]. Engaging in physical activity boosts NAD+ turnover, allowing your body to utilise it more effectively.

  • Cardiovascular workouts: Activities like running, walking, swimming, or cycling can enhance mitochondrial function and promote NAD+ synthesis
  • Resistance training: Aids in blood sugar regulation and minimizes oxidative stress
  • Rest: Quality sleep facilitates DNA repair and maintains hormonal equilibrium, both reliant on NAD+ dependent enzymes

Aim for a minimum of 150 minutes of moderate exercise weekly and aim for 7–9 hours of restorative sleep each night, as recommended by the NHS.

Reducing Stress to Protect Your NAD+ Levels

Chronic stress can reduce your NAD+ levels by increase inflammation and oxidative stress within the body. By nurturing your nervous system, you may be able to slow the decline of NAD+ and enhance your overall health.

Effective strategies for stress management [17][18]:

  • Engage in mindfulness, meditation, or breathing techniques
  • Ensure you are getting adequate sleep
  • Spend time in nature, exercise, or pursue creative activities
  • Reduce intake of stimulants such as caffeine and alcohol
  • Utilise saunas or warm baths - gentle heat may aid in NAD+ production
  • Maintain connections with friends, family, or a support network

Supplementation as an Additional Boost

In addition to making healthy lifestyle changes, many individuals opt to enhance their NAD+ levels through supplements. NAD+ injections and IV therapy are favored choices as they provide NAD+ directly into the bloodstream, resulting in quick and effective outcomes.

These methods can support your health, particularly during periods of stress, fatigue, or recovery. Combining lifestyle enhancements with supplementation may offer a more holistic strategy for improving well-being and maintaining energy levels over time.

What Is a NAD+ Supplement?

A NAD+ supplement helps restore levels of Nicotinamide Adenine Dinucleotide (NAD+), a vital molecule found in every cell. As we get older, our NAD+ levels naturally drop. This can affect energy, brain function, metabolism, and the body’s ability to repair itself.

NAD+ supplements are designed to top up these levels. They’re available as oral capsules, precursors like NMN or NR, patches, IV drips, or injections. Of these, NAD+ injections are among the most effective, as they go straight into the bloodstream for quick absorption and high bioavailability.

As with any supplement, how well it works can depend on your age, health, and lifestyle.

How to Use NAD+ Injections Safely

It’s important to use NAD+ injections safely to get the best results and avoid side effects. The NAD+ injection pen is made for easy self-use at home. Here’s a simple guide on how to set up, inject, and store your NAD+ safely and effectively.

Self-Injecting at Home: Essential Information

NAD+ pens provide a solution that is injected just beneath the skin (a subcutaneous injection). Administering each dose is straightforward by adhering to a few easy steps. To ensure optimal results and safety:

  • Administer the injection once daily for the initial three days (this constitutes your loading phase)
  • Following this, inject every other day as necessary
  • Recommended dosage: up to 50mg per injection, equating to 30 units on the pen (0.3ml)

How to Prepare Your NAD+ Injection Pen

Before beginning, allow the pen and cartridge to acclimate to room temperature for 2–3 minutes. After that, follow these straightforward steps:

  1. Remove the pen and cartridge from their packaging
  2. Take off the lid from the pen and unscrew the cartridge holder
  3. If the plunger is visible, gently press it into the base of the pen
  4. Insert the NAD+ cartridge into the cartridge holder
  5. Reattach the cartridge holder to the pen by screwing it back on
  6. Rotate the pen until the dosage meter is completely visible
  7. Press the dosage meter several times until the plunger hits the bottom of the cartridge and you feel some resistance

Your pen is now ready for use.

How to Administer Your Injection

To safely and effectively utilise your NAD+ injection pen, follow these steps:

  1. Attach a 6mm needle to the pen, keeping the needle cover on for the moment.
  2. Disinfect your selected injection area (stomach, thigh, or buttock) using an alcohol wipe.
  3. Take off the needle cover.
  4. Adjust the dosage meter to set your dose (e.g. 30 units = 50mg).
  5. Gently pinch the skin to lift it away from the muscle.
  6. Insert the needle just beneath the skin, maintaining a steady hand to prevent bruising.
  7. Press the button to administer the dose.
  8. Count to three, then withdraw the needle.
  9. Replace the cover on the needle and detach it from the pen.
  10. Reattach the pen lid and store it in the refrigerator.
  11. Dispose of the used needle in a sharps container.

Change your injection site each time to prevent skin irritation.

Common Reactions and What to Expect

It is common to experience mild side effects at the injection site, which are generally not a cause for concern:

  • Redness or a small amount of blood at the injection point
  • A residue of NAD+ solution remaining on the skin post-injection
  • Minor bruising if the needle shifts during the procedure

If you notice persistent or more severe symptoms, discontinue use of the pen and consult a healthcare professional.

How Frequently Should You Administer NAD+ Injections?

The frequency of your NAD+ injections is determined by your health objectives and routine. Here’s a basic guideline:

  • Loading phase: Administer once daily for the initial 3 days
  • Maintenance phase: Administer every other day, or as necessary

Each injection should not exceed 50mg (0.3ml). Always follow the instructions provided with your kit.

Best Practices for Storing and Using NAD+

Follow these tips to keep your NAD+ safe and effective:

  • Store the full kit in the fridge at 2°C to 8°C
  • Let the pen come to room temperature before each use
  • Keep the kit away from sunlight, heat, and moisture
  • Store safely out of reach of children and pets

Before using a vial, check for any expiry dates, discolouration, or floating particles. Do not use the solution if it looks off.

How to Refill Your NAD+ Pen

  1. Remove the pen lid and unscrew the clear section
  2. Push the plunger down to reset it
  3. Remove the used cartridge and dispose of it in a sharps bin
  4. Insert a new NAD+ cartridge into the clear section
  5. Reattach the cartridge section to the pen and use as normal

When to Seek Medical Advice

It is highly recommended to consult a healthcare professional before taking NAD+ daily to ensure the appropriate dosage and frequency based on your health needs and goals[10].

Additionally, while NAD+ injections are generally well tolerated, you should speak to a healthcare professional if you experience:

  • Persistent swelling, redness, or pain at the injection site
  • Signs of allergy – rash, itching, or breathing difficulty
  • Unusual fatigue, headaches, or digestive upset
  • Any symptoms that concern you or feel unusual

What's Included in the NAD+ Pen Kit?

Your injection kit includes everything needed for safe home use:

  • 1x NAD+ self-injection pen
  • 2x NAD+ solution cartridges
  • Micro-needles (6mm)
  • Antibacterial wipes
  • 1x Sharps bin for safe disposal

Side Effects: Are NAD+ Injections Safe?

NAD+ injections are generally well tolerated when used correctly and may offer several wellness benefits. Because NAD+ is a coenzyme already found in the body, supplementing it through injections is considered low risk for most healthy adults. However, as with any supplement, it's important to understand the potential side effects, interactions, and when NAD+ may not be appropriate.

Possible Side Effects and How to Manage Them

Most side effects from NAD+ injections are mild and short-term. They are typically related to the injection process rather than the NAD+ compound itself.

  • Redness or swelling: Common at the injection site; usually fades within hours.
  • Bruising: May occur if the needle is moved or the same site is reused frequently.
  • Stinging or discomfort: Often reduced by letting the solution reach room temperature before injecting.
  • Fatigue or flushing: Can occasionally occur after first-time use but generally settles quickly.

How to reduce side effects:

  • Clean the injection site with an alcohol wipe before each use
  • Rotate between injection sites to avoid skin irritation
  • Inject slowly and stay still during administration
  • Warm the pen to room temperature before injecting

If symptoms are persistent, unusual, or severe, stop using NAD+ and consult a healthcare professional.

Who Should Avoid NAD+ Injections?

While NAD+ is safe for many people, it may not be suitable in certain circumstances. You should avoid or delay use if you:

  • Are pregnant or breastfeeding
  • Have an active or recent cancer diagnosis
  • Are receiving chemotherapy or immunosuppressive therapy
  • Have known allergies to any component in the injection

Does NAD+ Cause Cancer?

There is no clear evidence that NAD+ directly causes cancer. However, NAD+ plays a role in both cellular repair and energy production pathways. This includes glycolysis, which cancer cells use for rapid growth. Some research suggests cancer cells may exploit NAD+ metabolism to support tumour progression.

At the same time, NAD+ is essential for DNA repair and has even been studied as a potential support in cancer treatment [11]. The relationship between NAD+ and cancer is complex and not fully understood. If you have a history of cancer or are at increased risk, consult a healthcare professional before starting NAD+ supplementation.

Combining NAD+ With Other Wellness Supplements

NAD+ injections can be used alongside other supplements as part of a holistic wellness routine. Common combinations include:

  • Vitamin B12: Often paired with NAD+ to support energy and cognitive function
  • Magnesium: Helps with muscle recovery and relaxation
  • NMN or NR: NAD+ precursors that may support long-term NAD+ levels
  • Adaptogens: Such as rhodiola or ashwagandha, for stress resilience

Does NAD+ Interact With Medications?

NAD+ may interact with certain medications or change how the body responds to them. For example:

  • Some antidepressants may affect NAD+ availability, potentially making supplementation less effective
  • NAD+ may influence insulin sensitivity, which could affect people managing diabetes
  • Other anti-ageing supplements may enhance the effects of NAD+, possibly requiring dosage adjustments

If you are taking prescription medication or other supplements, it's best to speak to a healthcare professional before adding NAD+ to your daily routine. This helps ensure there are no unwanted interactions.

NAD+ FAQs

Below, UK Meds has answered some of the most common questions that our customers ask us about NAD+ supplementation:

What Does NAD Mean In Medical Terms?

In medical terms, NAD stands for nicotinamide adenine dinucleotide. This is a coenzyme that is present in the human body. It exists in two forms: NAD+ (oxidised) and NADH (reduced), both of which play key roles in processes like energy production, DNA repair and cellular communication. As we age, NAD+ levels naturally decline, contributing to various health issues and age-related diseases.

It is important to note that NAD+ differs from the abbreviation "NAD", commonly used on NHS health records. This stands for "Nothing Abnormal Detected" [19].

Do NAD+ injections hurt?

The pain associated with NAD+ injections is typically minimal. You may feel a slight pinch or discomfort when the needle is inserted. Allowing the NAD+ solution to reach room temperature before you inject it can help reduce discomfort. Rotating injection sites can also prevent irritation and soreness.

Is NAD the Same as Vitamin B3?

NAD+ is not exactly the same as vitamin B3, but they are closely linked. Your body makes NAD+ from certain forms of vitamin B3. These include nicotinic acid, nicotinamide, and nicotinamide riboside.

These B3 forms help your body maintain healthy NAD+ levels. This is important for energy, cell repair, and many key functions in the body.

Can NAD+ Help with Hair Growth?

Yes, research shows that boosting NAD+ levels, especially through NMN supplements (a form that helps the body make NAD+), may support healthy hair follicles and improve hair growth and thickness.

NAD+ plays a key role in important cell functions like DNA repair, energy production, and managing oxidative stress (damage caused by free radicals).

Buy NAD+ Injections Online from UK Meds

Can I buy NAD+ Injections online in the UK?

Yes, you can purchase NAD+ injections such as NAD+ injections by Vivere from UK Meds. Always consult your healthcare provider or doctor before taking NAD supplements to ensure they are safe and suitable for your individual needs.

Do I need a prescription?

No, currently NAD+ does not require a prescription to purchase, meaning it is available over the counter. You should still always consult a medical professional before starting any supplements or treatments.

Which NAD+ injections are available at UK Meds?

UK Meds currently offer the NAD+ injection by Vivere. Vivere’s NAD+ pen is the only one made in a trusted UK MHRA-licensed, GMP-certified facility and supplied by an NHS-approved, UKAS-certified partner.

Learn more with UK Meds support resources for NAD+:

Sources

Author

Content author

Scott Weaver

Medical Content Writer • Bachelor of Arts Degree

Scott is an experienced, skilled medical content writer dedicated to creating helpful and accessible medical content for UK Meds.

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Medical Reviewer

Medical Reviewer

Alexis Missick

General Practitioner (GP) • MBChB

With over a decade of experience in the NHS and six years internationally, Alexis is a seasoned General Practitioner hailing from Turks and Caicos.

Read more

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