A Beginner's Guide to Aciclovir
Aciclovir is a commonly prescribed antiviral medicine used across the UK to treat a range of viral infections, particularly those caused by the herpes family of viruses. This guide explains what Aciclovir is, how it works, how to take it, its side effects and who can use it. You will also find guidance on interactions, costs in the UK and the most frequently asked questions about this medicine.
In One Sentence:
Aciclovir is an antiviral medicine used to manage infections caused by the herpes virus by slowing viral growth and easing symptoms.
Key Takeaways
Here are the five biggest takeaways from this beginner’s guide to Aciclovir:
What does Aciclovir treat? It is used to manage infections such as cold sores, genital herpes, chickenpox and shingles.
How does Aciclovir work? It slows viral replication, which helps symptoms improve more quickly.
How should I take Aciclovir? Follow the prescribed dose for your specific condition to achieve the best results.
What are the main side effects? Common effects include headache, dizziness, nausea and stomach discomfort.
Who can take Aciclovir in the UK? Most adults can take it, although some medical conditions require extra care.
What is Aciclovir (acyclovir), and what is it used for?
Aciclovir is an antiviral medicine used to treat infections such as cold sores, genital herpes, chickenpox, and shingles.
It works by controlling symptoms during outbreaks and helping them settle more quickly. It can be taken as a tablet, applied as a cream, or given as a liquid. Although many people use Aciclovir for common viral infections, it usually requires a prescription in the UK. It does not cure herpes viruses, but it helps manage flare-ups and reduce their severity.
How does Aciclovir work?
Aciclovir works by targeting viral replication, preventing the virus from multiplying as easily.
This slows the spread of infection within the body, helps symptoms improve and reduces the duration of outbreaks. It is most effective when taken at the earliest sign of symptoms, particularly for conditions like cold sores or genital herpes.
How Aciclovir Works
Condition | Mechanism of Action |
| Cold Sores | Slows the replication of the herpes simplex virus type 1 to reduce pain and healing time |
| Genital Herpes | Limits herpes simplex virus type 2 activity to control outbreaks |
| Shingles | Reduces varicella zoster viral load to ease nerve pain and shorten illness |
| Chickenpox | Slows varicella zoster replication to lessen symptom severity |
Aciclovir Dosage and How to Take It
Aciclovir should be taken exactly as directed by your doctor or prescriber because the dose varies depending on the type and severity of the infection [1].
Adults usually take Aciclovir two to five times a day, depending on their condition. Swallow the tablets with water and try to space the doses evenly throughout the day. Completing the full course is important even if symptoms improve early.
Typical Adult Doses
Condition | Typical Adult Dose |
| Cold Sores | Usually 200mg five times a day for 5 days |
| Genital Herpes Outbreak | Usually 200mg five times a day for 5 days |
| Genital Herpes Suppression | Usually 400mg twice daily |
| Shingles | Usually 800mg five times a day for 7 days |
| Chickenpox | Usually 800mg four times a day for 5 days |
Aciclovir Side Effects
Most people tolerate Aciclovir well, although some side effects can occur, especially at higher doses. The most common effects include:
Nausea
Stomach Discomfort
Headaches
Dizziness
Rash
Severe reactions are rare but require urgent medical attention, particularly if there are signs of an allergic response.
Side Effects Table
Side Effect | Description | What To Do |
| Headache | Pressure or pain in the head | Rest, drink water, seek advice if persistent |
| Nausea | Feeling sick or queasy | Take Aciclovir with food if helpful |
| Diarrhoea | Loose or watery stools | Stay hydrated and seek advice if severe |
| Dizziness | Lightheaded feeling | Avoid driving until symptoms stop |
| Rash | Skin irritation or redness | Seek advice if severe |
Warnings and Precautions
Aciclovir may not be suitable for people with kidney problems, weakened immune systems, or dehydration [2].
Tell your doctor about any existing health conditions before starting treatment, particularly if you are elderly, pregnant, breastfeeding, or taking long-term medicines. Hydration is important, especially when taking higher doses.
Interactions
Aciclovir can interact with certain medicines, including those that affect kidney function or are concentrated in the kidneys [3].
Tell your doctor if you take any prescription or over-the-counter medicines. Herbal supplements should also be discussed to ensure they do not affect Aciclovir’s safety or effectiveness.
Who can take Aciclovir? (Eligibility Criteria in the UK)
Most adults can take Aciclovir, although people with kidney problems, neurological disorders, or immune system conditions may need dose adjustments [4].
Children can take Aciclovir for some infections, but a doctor must carefully assess the dose. Pregnant and breastfeeding women should only take it if a healthcare professional advises it is safe.
Aciclovir Cost in the UK
Aciclovir prices vary depending on the strength, quantity and supplier.
Typical UK Prices
Strength | Typical Prices (Subject to Change) |
| 200mg Tablets | Ranges from low-cost generic prices to moderate prices, depending on pack size |
| 400mg Tablets | Usually slightly higher than 200mg |
| 800mg Tablets | Higher cost bracket due to usage in more severe infections |
| Cream | Low to moderate cost, depending on size |
Aciclovir FAQs
How long does Aciclovir take to work?
Aciclovir usually starts working within a few hours, although symptoms may take a few days to improve.
Most people experience early symptom relief, but full recovery depends on the severity of the infection and how soon treatment begins.
Can I drink alcohol while taking Aciclovir?
Yes, you can drink alcohol while taking Aciclovir because alcohol does not affect how the medicine works.
However, heavy drinking may slow recovery or worsen dehydration, so it is sensible to limit alcohol during treatment.
Can I take Aciclovir with paracetamol?
Yes, you can take Aciclovir with paracetamol because the two medicines do not interact.
This combination is often used for shingles or chickenpox to manage pain and fever. It is important that you stay hydrated when using both medications.
Should I take Aciclovir with food?
You can take Aciclovir with or without food, although taking it with meals may help reduce nausea.
If you experience stomach discomfort, pairing doses with food often improves tolerance.
Can I buy Aciclovir over the counter in the UK?
No, you cannot buy Aciclovir tablets over the counter in the UK because they require a valid prescription.
Aciclovir cream for cold sores is sometimes available without a prescription, but oral forms are prescription-only.
Final Thoughts From Our Clinical Team
Aciclovir is a trusted antiviral medicine that helps manage a range of viral infections by slowing viral replication and easing symptoms. When used correctly, it is effective, safe for most people and available in the UK. Understanding how to take it, what to expect and when to seek advice ensures you get the most benefit from your treatment.
Sources
[1] How and when to take or use aciclovir - NHS
[2] Who can and cannot take or use aciclovir - NHS
[3] Taking or using aciclovir with other medicines and herbal supplements - NHS
[4] Aciclovir 200mg Tablets - Patient Information Leaflet (PIL) - (emc) | 2353
Blog author
Scott Weaver
Scott is an experienced and professional content writer who works exclusively for UK Meds.
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